Shortcuts

All shortcuts are listed under Hotkeys in your settings. The spell shortucts aren't listed in this guide, they're bound to 1 through 0 on the keyboard and can be found in hotkeys settings.
Using shortcuts considerably speeds up your ingame actions

I - Character Info

U - Reputation

K - Currency

P - Spellbook

N - Talents

L - Quest Log

B - Bag

F12 - Bag and Character Info

M - Map

G - Social

R - Autorun

T - Object highlighting
Z, X, C - Context actions, usable when context icons appear between your first and second set of spells at the bottom of your screen

Enter - Chat window

F1 - Selftargeting

F2 - Target 1st group member

F3 - Target 2nd group member

F4 - Target 3rd group member

F5 - Target 4th group member

F6 - Target 5th group member

Tab - Change target

F - Assist Target

Alt+Z - Hide interface

Prnt Scrn - Screenshot
Esc - Settings